Five things you need to know today, and disaster movies

Good morning, Boston, and RIP, Bishop Desmond Tutu. Here are the five things you need to know to start your busy workday. The drug trial that changed it all Don Seiffert reports on a drug trial that began 10 years ago, whose effects can still be seen today in the way biotech companies approach drug development for rare diseases. 'Future-proofing' antibody variants Rowan Walrath spoke spoke to Abpro Corp. CEO Ian Chan about his company's Covid drug candidate, which hopes for FDA approval in 2022. Airlines…